Gastroenterology and Digestive Disorders Conference

Acute Kidney Injury

AKI is a condition in which the glomerular filtration rate is abruptly reduced, affecting a sudden retention of endogenous and exogenous metabolites (urea, potassium, phosphate, sulfate, creatinine, administered drugs) that are normally cleared by the kidneys. Acute kidney injury and its immediate complications, such as water retention, high acid and potassium levels in the blood, and increased urea nitrogen in the blood, can often be treated successfully. Typically, prognosis is favorable for people whose acute kidney injury is due to decreased blood flow because body fluids have been lost through bleeding, vomiting, or diarrhea—conditions that are reversible with treatment. Some complications of acute kidney injury are serious and may even be life-threatening. People may need to be treated in a critical care unit (also called an intensive care unit, or ICU). Acute kidney injury may be prolonged, necessitating removal of waste products and excess water. Waste removal can be done through dialysis, usually hemodialysis. 

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