Ophthalmic Drug Delivery

The major challenge for pharmacologist and formulation scientist is ocular drug delivery. New ophthalmic drug delivery systems developed to address the need for long-term drug delivery from a single procedure and to potentially reduce adverse events associated with some of the more potent therapies.

Various strategies for ocular drug delivery include the formulation techniques for improving the availability of drugs; viscosity enhancers and mucoadhesives aid drug retention and penetration enhancers promote drug transport into the eye. The drug-loaded contact lenses and ocular inserts also used that allows drugs to be better placed where they are needed for more direct delivery. Nanospheres is that the technology that gives potential for drug delivery to the eye within the least volume, but along with this technology, a number of factors required into consideration including retrievability, tolerability of each the drug and also the delivery device, ability of the device to remain in position once injected and durability in the eye beyond drug delivery.

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