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Professor Ningli Wang

Professor Ningli Wang

Director of Beijing Tongren Eye Center /President of Chinese Ophthalmology Society

Title: Canaloplasty for POAG with Failed Filltering Surgery

Biography

Biography: Professor Ningli Wang

Abstract

Canaloplasty for POAG with failed filtering surgery: Glaucoma is a leading cause of irreversible blindness. For many patients, surgical intervention is finally necessary to preserve the remaining vision. Glaucoma filtering surgery (GFS) is the main choice, which creates constant shunting of aqueous from anterior chamber into newly built subconjunctival space. Despite a great improvement, GFS has documented high complications and failure rate especially for primary open angle glaucoma (POAG) received repeated GFS, who runs higher risk of bleb insufficiency. Canaloplasty, a new non-filtering, bleb-free method, provides good IOP reduction with a favorable safety profile for POAG as initial procedure. We practiced 24 canaloplasty on POAG with failed GFS. For 18 patients with intact SC, a standard canaloplasty was done. Circumferential catheterization achieved in 89.2% eyes. In one year, IOP decreased by 34.1% (from 28.3±8.4 to 15.5±2.5 mm Hg), with topical medication reduced from 2.9±0.7 to 0.7±1.5. Surgery rate was 52.4% for complete success and 77.4% qualified criteria, both of which were similar as canaloplasty as an initial procedure. For patients with broken SC, we proposed modified canaloplasty, relying on our new technique of relay suture guided by illuminated trocar. Circumferential catheterization achieved in 83.3% eyes. At 9-months, IOP reduced to 17.7±4.5 mmHg and mean glaucoma medication use was 1.0±1.0 (baseline values were 32.5±5.2 for IOP and 3.2±0.4 for medication). For both groups, hyphema and clinically detectable bleb were the most common complications. According to our results, canaloplasty is a new, efficient and safe option for POAG with failed GFS.