Microbiologists 2018

Cancer and Pharmacology

Treatment often fails when cancer becomes resistant to anti-cancer drugs. Thus, drug resistance is a big challenge facing the survival of cancer patients. Research in discovering and designing drugs with new chemistry structure or mechanism of action is critical to overcome the drug resistance problem and give patient better chance to survive longer. Monoclonal antibody therapy is a form of immunotherapy that uses monoclonal antibodies (mAb) to specifically bind to specific cells or proteins. Nanomedicine is the application of nanotechnology which made its debut with greatly increased possibilities in the field of medicine. Nanomedicine desires to deliver research tools and clinically reformative devices in the near future.The clinical toxicology importance of any drug interaction depends on factors that are drug-patient and administration related. Generally, a doubling or more in plasma drug concentration has the potential for enhanced adverse or beneficial drug response Drug interactions in oncology are of particular importance owing to the narrow therapeutic index and the inherent toxicity of anticancer agents. Interactions with other medications can cause small changes in the pharmacokinetics or pharmacodynamics of a chemotherapy agent that could significantly alter its efficacy or toxicity.