13^th Global Dermatologists Congress July 23-24, 2018 Moscow, Russia

Biography:

Prof.Dr. Ospan A Mynbaev has completed his PhD and ScD studies in Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Russian Health Ministry in cooperation with Petrovsky Russian National Center of Surgery and Lomonosov Moscow State University followed with postdoctoral studies in Belgian universities (KULeuven, Ghent University, VUB). Recently he established an international alliance of researchers from basic sciences and medical practitioners named “The International Bureau of Human Body Design & Biomodeling” at the MIPT. His research interests include surgical topics closely related to multidisciplinary translational research and personalized medicine. He developed new generation of training kits for medical education based on hand skills manipulation & ultrau modern technologies especially designed for cosmetologists and plastic surgeons.

Abstract:

In this new generation of training technology for medical education combined hand-manipulating and IT master class will be presented by the International Bureau of Human Body Design & Biomodeling Alliance and iBellaInt Ltd. from Moscow Institute of Physics and Technology (State University). This state-of-the-art technology is opening a new era in medical education where surgeons can gain hand-manipulation skills by means of a unique training kit, which is a combination of hand-training tool with electronics, IT and telemedicine. Surgeons can see target structures under the skin while performing manipulation on real facemodel by using real routinely used instrument-syringe on the monitor. Surgeons will see moving of their instrument-syringe needle inserted under the skin, its movement contour during procedure, injection site of medication in the right place—target muscles or wrong places—vessels, nerve fibers, lymphatic drainage structures with complications. Special electronic devices and software were realized between face-model and PC with remote monitor via internet with our server in order to realize real time visualization technology during hand manipulations. Efficiency of training is going to be analyzed by a special program based on principles of artificial intelligent development by programmers from department of artificial technology and robotics. Master class can be translated by simultaneous internet connection to elsewhere by choice of the organizing committee. In conclusion, the state of the art training technology for medical education combined hand-manipulating and IT will give understanding of unique next generation educational and training technology principles for all surgical disciplines, especially for cosmetology, plastic surgery and nursery.

Biography:

PhD Sylwia Nawrot Doctor of cosmetology in Poznan University of Medical Sciences, visagist, stylist, specialist in micropigmentation and health promoter, creator of several author’s techniques with more than 10-years of work experience.

Sylwia Dobrowolska Visagist, nailart specialist, PMU master, creator of several author’s techniques. Specialist in microblading, trichopigmentation, Rejuvi Tattoo Removalmethod and needling

Abstract:

Corrective permanent makeup, colloquially referred to permanent makeup, is among others, a supportive form of a surgical treatment, in cases when the cosmetic and aesthetic effects of surgical procedures are unacceptable to patients. The task of permanent make-up is to restore a natural, healthy look. Corrective makeup therapy is an important supportive method of a long-term
medical treatment, as well as a therapeutic alternative for patients. It is especially important because patient’s psychological satisfaction is an important factor increasing the effectiveness of medical treatment and allows the patient to recover faster. One of the forms of such therapy may be non-surgical reconstruction of areolas and nipples with dynamically developing techniques of medical pigmentation. Breast reconstruction surgery allows women after mastectomy to regain the psychological well-being. Research shows that more and more women are deciding to have a breast reconstructed procedure. Bust reconstruction surgery is a multi-factorial process, which consists mainly of reconstructing breast prominence and creating symmetry in relation to the other breast. Breast reconstruction is usually performed on women after breast amputation due to cancer or women affected by Poland syndrome characterized by unilateral hypoplasia (incomplete development) or aplasia (absence) of the chest muscles and areolas, as well as after chest burns. Reconstruction of the natural appearance of the chest is extremely important for aesthetic and physical as well as psychological reasons. There are a lot of reasons why women decide to have a breast reconstruction procedure, but the most important thing is a return to their normal body structure and getting rid of memories related to the illness. It creates a chance for effective rehabilitation and full return to functioning in a society. Reconstructive surgery treatments sometimes are finished with the surgical reconstruction of areolas. But often happens that the effect does not give the patient satisfaction and the colour become pale and disappears completely, which forces to the search for other corrective methods. One of the less invasive techniques of non-surgical reconstruction of the areola is the micropigmentation which is the injection of a pigment directly under the epidermis with a needle, and thus the result is the pigmentary reconstruction of the breast gland structures. The aim of the work is to show the effects of pigmentation and general principles of the procedure, with particular emphasis of the latest technique of work in medical and aesthetic pigmentation

Biography:

Adolfo Napolez M.D. graduated from Southern Illinois University School of Medicine followed by a General Surgery Residency at West Penn Hospital in Pittsburgh, Pennsylvania, and followed that up with a Burn Surgery Chief Residency at Cook County Hospital in Chicago, Illinois and finally a two year Fellowship in General Cosmetic Surgery, highlighting Asian Cosmetic Surgery. He is a member of the American Academy of Cosmetic Surgery, American Society of Cosmetic Breast Surgery, as well as a member of the California Academy of Cosmetic Surgery. Dr. Napolez has published articles in 5 different Medical Journals, as well as a chapter Author in a textbook on Asian Facial Cosmetic Surgery. He has twice been selected as one of America’s Top Surgeons in Cosmetic Surgery, as well as a Top Doctor in Plastic Surgery Practice Magazine.

Abstract:

Asian eyelids have several characteristics that distinguish them from the eyelids of people from European and African descent. These include: 1) low, poorly defined or absent lid creases, 2) pronounced fullness to the upper and lower lids, 3) narrow palpebral fissures and 4) epicanthal folds. The extent to which these anatomic variants are present, determines the height and prominence or absence altogether of the upper lid crease in the Asian eyelid. Asian blepharoplasty is the most common Cosmetic Surgery procedure done in the Far East, with many variants noted. The discussion will include the patient
selection, preparation, anesthesia, and surgical technique utilized in the operation for the creation of the double eyelid in the patient.

Biography:

Marian Dmochowski—MD/PhD—is the Head of Autoimmune Blistering Dermatoses Section, Department of Dermatology, Poznan University of Medical Sciences, Poznan, Poland. His research interests are focused on autoimmune blistering dermatoses, particularly issues of improving diagnosing them with imaging and biochemical-molecular techniques, their comorbidities and improving management. His publications were cited almost 1,000 times. He is an active Member of the Society for Investigative Dermatology (USA).

Abstract:

Autoimmune blistering dermatoses (ABDs) require precise diagnosis as generally aggressive therapies having potentially lethal side-effects are necessary. Nowadays, they can be reliably diagnosed using a combination approach with both imaging and biochemical-molecular techniques. Taking into account cost effectiveness, I am using an imaging technique with singlestep direct immunofluorescence (DIF) of perilesional tissue and DIF of plucked scalp hair which is appropriate for evaluation of IgA, IgG, IgM, C3 as well as IgG4 and IgG1 subclasses deposits. Dew drops on spider web appearance is newly named by me, diagnostically valuable and putatively having implications for treatment, pattern of Th2-dependent IgG4 deposition in
pemphigus diseases at an active-stage with DIF techniques. In addition to DIF, still the golden standard for diagnosing ABDs, serum studies using biochemical-molecular techniques, namely ELISA, are necessary. Currently, the author is using a multianalyte ELISA enabling the detection of IgG antibodies to desmoglein 1, desmoglein 3, BP180, BP230, envoplakin and type
VII collagen in a single procedure. In case of clinical suspicion of dermatitis herpetiformis an ELISA for serum IgA antibodies to tissue translglutaminase, instead of multi-analyte ELISA, is used in addition to DIF. Such a dual imaging/biochemicalmolecular approach is usually sufficient to detect autoimmune nature of a blistering dermatosis in question, enabling one to
resign from performing H+E histology and indirect immunofluorescence studies. Despite substantial progress in diagnosing ABDs heading toward all-in-one methodology, treatment schemes are still unsatisfactory. The aim of future therapeutic efforts should be based on a personalized medicine principle.

Biography:

Bettina Rümmelein, after completing her Residency as a Dermatologist and Allergologist at the University Hospital Hamburg-Eppendorf, Germany, with internships at Stanford University, Palo Alto and the Mayo Clinic, Rochester, USA, worked for two years in a large group practice in Frankfurt. From 1998 to 2008, she ran her own private practice near Frankfurt. After moving to Switzerland, she worked at the University Hospital Zurich for eight years, where she directed the clinic for Aesthetic Dermatology and Laser Medicine for three years. Since April 2014, she dedicated herself exclusively to the work in her own clinic. She is licensed for laser treatments and accredited by the Laser Commission as a training center. Aesthetic and Laser Medicine have become her main topics of interest in recent years. Her clinic offers the full range of state-to-the-art laser devices that are used in dermatology. As President of the Swiss Society for Medical Laser Applications (SGML), she takes responsibility for the Swiss Laser Congress.

Abstract:

Introduction: Permanent makeup (PMU) is a frequently performed cosmetic intervention performed by beauticians. Technically spoken it is a facial tattoo. Failed drawings or changed customers’ acceptance lead to the desire of removal.

Materials & Methods: The possible options for PMU removal and coverage have been collected and evaluated in 87 individual cases. In treatable cases, laser treatments with q-switched Nd:YAG laser have been performed.

Results: In 52 out of 87 cases laser treatments could be performed. 1–12 treatments were necessary to remove the PMU. In three cases, color resisted laser treatments. In two cases laser treatment had to be interrupted due to colour change into greenblue.

Discussion: In laser, PMU removal test shots have to be obligatory because colour changes can cause severe esthetic problems. Covered up PMU (skin colour) is particularly dangerous for colour change. Heat induced shrinking of eye area can cause ectropium. Surgical solutions have to be taken in consideration. The presentation tries to set up some guidelines for the treatment of failed PMU

Biography:

Gitta Neufang has completed her PhD from the University of Hannover in cooperation with the German Cancer Research Center in Heidelberg on mechanisms of nonmelanoma skin cancer. After two years as a post doctorial research fellow at the Univeryity of Münster, she joined the research department of Beiersdorf AG, Hamburg focussing on sensitive skin and skin diseases with a strong interest in the neurophysiology of the skin. Since 2014 Gitta Neufang is the global Head of Medical Management.

Abstract:

Atopic dermatitis is a chronic, relapsing inflammatory skin disease characterized by skin barrier defects and the burden of itch. In order to increase patients´quality of life, emollient-based skin care is the basis of all treatments. We provide clinical and scientific evidence that tailored skin care adapted to the phases of atopic dermatitis is able to break the itch-scratch cyle in a targeted way. To investigate anti-pruritic pathways and mechanisms in atopic skin, we developped an innervated topic 3-dimensional skin model allowing the investigation of the cross-talk between sensory nerve endings and atopic skin cells (Roggenkamp et al, JID 2013). In this model, atopic keratinocytes released elevated level of nerve growth factor (NGF) resulting in nerve fiber sprouting, enhanced release of the neuropeptide calcitonin-gene-related peptide (CGRP) and epidermal thickening. Consequently, the atopic innervated skin model resembled the atopic phenotype in vivo with hyperinniveration and
epidermal hyperplasia. Further studies implied that theactivation of the cold receptor TRPM8 can modulate NGF expression in atopic skin cells. The menthol-derivative and TRPM8 activator Menthoxypropanediol (MPD) reduced NGF expression and consequently hyperinnervation in atopic skin models(Roggenkamp. et al, EXP DERM 2016). As hyperinnervation has been associated with itch in atopic dermatitis, these results mechanistically indicate anti-itch efficacy of MPD in vitro. a proof of concept study (randomized, double blind, vehicle controlled) demonstrated that the treatment with a cooling compound including TRPM8 agonist MPD reduces chronic pruritus in xerotic skin (Ständer et al, JEADV 2016). Theses results were confirmed in a investigator-blinded study to assess the efficacy of a water-in-oil emulsion containing anti-inflammtory licochalcone A, anti-bacterial 1,2-Decanediol, anti-itch active MPD demonstrating a reduction in the lesional severity and
S.aureus colonization as well as improvement of the barrier function parameters in volunteers with mild to moderately severe AD (Angelova-Fischer et al., JEADV 2014). These results emphazise that application of clinical evidence-based pro-active skin care significantly improves atopic dermatitis patient´s quality of life.

Biography:

Swami Shraddhamayananda is the Monk in Charge of the Medical Unit at Belur Math, Ramakrishna Mission, Belur, Howrah, West Bengal, India. He is now engaged in the study of alternative medicines particularly the homeopathic medicines on different skin diseases and he is now running a separate clinic for this purpose which is at present attaended by hundreds of patients daily. He has published 12 papers on various skin diseases in peer reviewed journals and published a book on vitiligo which has been translated in more than 10 different languages

Abstract:

In general, about 7–12% human beings are suffering from skin warts following human papilloma virus infections. Besides verruca vulgaris, the commonest type of wart, planter and flat warts are also not uncommon. The natural cure of warts usually takes about 1–2 yrs time, during which the affected person suffers from cosmetic disfigurement which is most often associated with pain and during this long period it remains as a potent source of transmission to others. Thus, it is important to get rid of this disease as soon as possible. In this study, 200 patients suffering from different types of skin warts were treated with ultradiluted homeopathic medicines without any known side effects in human beings, to see whether this treatment can ameliorate the disease earlier. Following proper counseling as per institutional ethical committee guidelines, all demographic evidences of the patients were recorded along with history, wart type , and other clinical findings. Three homeopathic medicines Thuja oc. 1000, Dulcammara 100 and Nat. Mur 1000) were used in this study which were administered orally. Homeopathic medicine “Thuja” was given highly proliferated warts; “Nat. Mur.” was given in palm and sole warts, while “Dulcammara” was given in other types. After treatment with these medicines, in 88% cases remission started within a month and within three months all these patients were cured from warts. In 12 patients, remission was delayed and the remaining 12 cases discontinued treatment. Thus, the results of this study were very encouraging. It not only gave immense relief to the suffering humanity but it also prevents the spread of the disease. As some warts were precancerous lesions it also gave protection from developing malignant transformation of the warts.

Biography:

Uzma Rajar is currently working as an Associate Professor in the Section of Dermatology at Isra University Hospital Hyderabad. She holds a MBBS degree from Liaquat University of Medical & Health Science, a Liaquat University of Medical & Health Science, D.D.Sc in Dermatology from University of Wales (U.K), and a M.Sc in Dermatology from Cardiff University. She has done her internship in the Dermatology Department at LUMHS Hospital..

Abstract:

Objectives: Compare the efficacy of olive oil and placebo (alterative) in the topical treatment of penile lichen planus.

Methods: A randomized, double-blind, placebo (alterative)–controlled trial was designed. Thirty patients were randomized into two groups to receive olive oil or placebo for 12 weeks.

Results: Thirty consecutive male patients participated in the study. We found annular ring like patterns as a single or multiple lesions and ulcerative lesions with and without pain in 69% and 31%, respectively. The most common site of penile lichen planus was the tip of the penis. Six out of fifteen patients treated with olive oil (40%) had a good response after 12 weeks of treatment, while two of 15 alternative-treated patients (14%) had a similar response (P<0.001). Furthermore, one patient treated with olive oil (7%) had a complete clinical remission. Clinically, penile lichen planus improved by at least 40% (good response) in six patients treated with olive oil and in two patients treated with placebo (alternative) 14% (good response) (P<0.001). No side-effects were found in both groups.

Conclusions: Olive oil is significantly more effective for clinical improvement of penile lichen planus than placebo (alternative). Therefore, olive oil can be considered as a safe treatment for patients with penile lichen planus.

Biography:

Iqbal Bukhari is a Professor and Consultant Dermatologist with more than 29 years of experience in many dermatological diseases and their management. His special interests are in laser therapy, phototherapy, dematopathology, cosmetic dermatology and study of genetic diseases. Has many publications in various international medical journals. He has a certification of added qualification in Cosmetic and Laser Procedures, 2013; King Faisal Fellowship in Dermatological Diseases, College of Medicine, King Faisal University, Dammam, Saudi Arabia, 1994; MBBS, King Faisal University, Dammam, Saudi Arabia, 1989; certificate in Alternative Medicine Therapy from Wagner College in USA, 2004 and certificate in Acupuncture Therapy from Flamel College in USA, 2004.

Abstract:

A 69-year-old southern Arabic female presented to our dermatology clinic at King Fahd Hospital of the University as a follow-up case of lipedematous scalp diagnosed in our clinic in 2003. She is a known case of supraventricular tachycardia and hypercholestermia well controlled with medication. Besides, the patient’ scalp condition was last evaluated four years prior to her current visit in our clinic with no significant change. Interestingly, on examination of the scalp, there was absence of the spongy feeling on palpation and there was no loss of hair. Routine blood tests were normal. Axial computed tomography of the skull showed scalp thickness in the high occipitoparietal region of 8 mm as compared to 21.1 mm in 2003, while mid sagittal reconstructed computed tomography showed a scalp thickness at the high occipitoparietal region of 9 mm as compared to 16.9 mm in 2003. Subcutaneous fat thickness was almost 6 mm at the occipitoparietal region which is normal compared to 19.2 mm reported in 2003 in the same region. Hence, we confirmed our impression of spontaneous complete resolution of lipedematous scalp after 13 years duration.

Biography:

Jianyun Lu is the Professor and Chair of the Department of Dermatology, The Third Xiangya Hospital of Central South University, and Visiting Scholar of Dermatology of Northwestern University. She is also the Standing Committee Member of the Branch of Dermatology and Immunology of China Association of Chinese Medicine. Her main research interests include the pathogenesis of atopic dermatitis and its intervention; study on clinical application and mechanism of medical ozone and Cosmetic Dermatology.

Abstract:

Background: Atopic dermatitis (AD) is an inflammatory skin disease characterized as Staphylococcus aureus (S. aureus) colonization as well as an imbalanced immune response. Current research shows that topical ozone therapy is an effective and alternative treatment in the management of multiple skin diseases, including AD. However, the mechanism for the ozone is
not clearly understood.

Methods: Patients between 6–65 years old diagnosed with moderate or severe AD were treated topically with ozone. The treatment scheme is topical application of ozonated water followed by ozonated oil, twice daily, for two weeks. The Severity Scoring for AD (SCORAD) index, Visual Analog Scale (VAS) pruritus and sleep scores were evaluated. The thickness of epidermal layer was detected by Reflectance Confocal Microscopy (RCM) and the expression of Th1, Th2, Th17 and Treg type cytokines in peripheral blood was tested by ELISA. Plate cultivation was used to quantitatively detect numbers of S. aureus colonizations in skin lesions.

Results: Twelve patients in the present study showed significant improvement in the eczematous skin lesions, with better keratinization of the stratum corneum, clearer basal layer structure and reduced infiltration. of inflammatory cells SCORAD, VAS pruritus and sleep scores were all significantly decreased (p<0.01). The ozone decreased the numbers of S. aureus colonization in skin lesions after treatment (90.74±0.14) % (P< 0.01). By using ELISA, we detected several cytokines concentrations in the serum in the patients. It was found that IL-17A expression was significantly decreased after treatment with ozone (p<0.01). On the other hand, although ozone increased the level of suppressive cytokine, IL-10, and decreased the level of pruritus related cytokine, IL-31, no significances were found (p>0.05).

Conclusion: The treatment by using topical ozone alone significantly improves eczematous lesions in patients with AD. The mechanisms involved might be related to rapid reduction of S. aureus colonization and decreasing IL-17A expression. Our findings suggest that topical ozone therapy may be a potential remedy for AD.

Biography:

Iqbal Bukhari is a Professor and Consultant Dermatologist with more than 29 years of experience in many dermatological diseases and their management. His special
interests are in laser therapy, phototherapy, dematopathology, cosmetic dermatology and study of genetic diseases. Has many publications in various international medical journals. He has a certification of added qualification in Cosmetic and Laser Procedures, 2013; King Faisal Fellowship in Dermatological Diseases, College of Medicine, King Faisal University, Dammam, Saudi Arabia, 1994; MBBS, King Faisal University, Dammam, Saudi Arabia, 1989; certificate in Alternative Medicine Therapy from Wagner College in USA, 2004 and certificate in Acupuncture Therapy from Flamel College in USA, 2004

Abstract:

Background: Knowledge on the association between patient beliefs and their concerns towards systemic medication and treatment adherence in patients with chronic inflammatory diseases (IMID) is limited. Therefore, ALIGN (3D-digital scannining technique) was conducted to provide real-world data in either of the analyzed conditions.

Methods: ALIGN was a cross-sectional, multi-country epidemiological study conducted in over 7,300 patients to describe patient’s beliefs with various IMID towards systemic medication and correlate patient’s beliefs with disease characteristics, adherence levels, or patient perception parameters. Tools used included, the Beliefs about Medicines Questionnaire (BMQ), and the 4-item Morisky Medication Adherence Scale (MMAS-4). This poster displays data on the subgroup of patients documented in Lebanon and Saudi Arabia.

Results: 263 patients were analyzed in this country-specific subgroup. Therapy with TNFi (as mono or combination therapy) appeared more effective than conventional therapy, leading to complete response in more than 61% (vs. 30.3%). BMQ concern perception increased with perceived harm of medications, expected illness duration, perceived emotional involvement and risk of depression. BMQ necessity perception increased with age, expected illness duration, perceived treatment control and risk of depression. Necessity was higher in patients taking TNFi compared to those treated with conventional medications alone. In addition, the chance of being highly adherent was positively correlated with the necessity score.

Conclusions: Main results of this subgroup of Lebanese and Saudi Arabian patients are largely in concordance with the results of the overall population. Necessity beliefs were highest in patients treated with TNFi and positively correlated with high adherence.