6th World Pharmacists & Clinical Pharmacy Annual Congress
Chicago, USA
Norbert Nwankwo
University of Port Harcourt, Nigeria
Title: Digital signal processing-based techniques: Providing pharmacists with computerized procedures for investigations
Biography
Biography: Norbert Nwankwo
Abstract
Background: Pharmaceutical dispensing practice has benefited from computerized, motorized (robotics) and Information Technology-based devices including Automated Dispensing Cabinets. Such devices are needed for pharmacological assessments. We had already developed one called Computer-Aided Pharmaco-Investigator.
Aim: The purpose of this presentation is to demonstrate to pharmacists how Pharmaco-Investigator works using potency assessments of two Anti-retroviral agents called Enfuvirfide and Sifuvirfide, and their protein target, N-terminal Heptad Repeat (NHR).
Method: The sequences of above-named agents are processed using a Digital Signal Processing (DSP) approach called Informational Spectrum Method (ISM) and nine pharmacological (physio-chemical and structural) parameters engaged.
Discussion: As shown in table 1, Sifuvirtide demonstrated greater potency than Enfuvirtide. This is in accord with the outcome of previous clinical investigation. This procedure is employable on all drugs as they are known to be either proteins, have protein targets or proteins encircling them.
Conclusion: This computerized (rational) and reliable device, which is employable on all drugs and is based on DSP technique that has served mankind for decades in areas such as radar technology has the tendency to revolutionalize pharmacological assessments.