Biography
Biography: Marco Manfredi
Abstract
Stomach was considered for many years a sterile environment due to its acid secretion which was thought to represent a barrier against microorganisms’ development. But since the discovery of Helicobacter pylori at early 80's, studies’ regarding gastric microbiota has been evidently increased. Helicobacter pylori are now considered the first trigger for the development of the carcinogenetic cascade that leads to gastric ADK. But it is not solely responsible. It seems that it is a trigger causing the alterations of gastric microbiota that result in the development of ADK. Restoring the gastric microflora or maintaining a physiologic gastric environment could be a way to avoid the carcinogenetic cascade. Furthermore we will highlight the results of our study on probiotics and Helicobacter pylori infection. rnrn