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Pranaya Mishra

American University of the Caribbean School of Medicine, Netherlands Antilles

Title: Impact assessment of pharmacist-supervised intervention on health-related quality of life of newly diagnosed diabetics in Nepal: A randomized controlled trial approach

Biography

Biography: Pranaya Mishra

Abstract

Patients’ knowledge and self-care skills of diabetes are corner stone to improve their health-related quality of life. The study aimed to assess the impact of pharmacist-supervised intervention through pharmaceutical care program on health-related quality of life of newly diagnosed diabetics in Nepal following a non-clinical randomized controlled trial approach.

Materials & Methods: An interventional, pre-post non-clinical randomized controlled trial was conducted among randomly distributed 162 [control (n=54), test 1 (n=54) and test 2 (n=54) groups] newly diagnosed diabetics by a consecutive sampling method for 18 months. An ADDQoL questionnaire investigated patients’ health-related quality of life scores at baseline, three, six, nine and twelve months. Test groups’ patients received pharmaceutical care while control group patients were under physician/nurse’s care. Non-parametric tests i.e., Friedman test, Mann-Whitney U test and Wilcoxon signed rank test were used to find the differences in average weighted impact scores among the groups before and after the intervention (p≤0.05).

Results: Friedman test identified significant (p<0.001) improvement in average weighted impact scores among test groups’ patients. However, differences in scores were significant between test groups at 6-months (p=0.033), 9-months (p<0.001) and 12-months (p<0.001); between control and test 1 groups at 12-months (p<0.001) and between control and test 2 groups at 9-months (p<0.001) and 12-months (p<0.0010) on Mann-Whitney U test.

Conclusions: Pharmaceutical care intervention significantly improved average weighted impact scores of diabetics in test groups compare to control group. This signifies the improvement in health-related quality of life of test groups’ patients and hence describes the pharmacist’s contribution and key role in Nepali healthcare system.