Sibel Catirli Enar
Turkiye Hospital, Turkey
Title: The right heart in heart failure with preserved ejection fraction
Biography
Biography: Sibel Catirli Enar
Abstract
Heart failure with preserved ejection fraction (HFpEF) affects nearly half of the patients with clinical signs of heart failure.HFpEF is considered to be a disease of the left ventricle (LV). It is characterized by impaired diastolic function due to to abnormal relaxation and increased chamber stiffness.The role of right ventricle (RV) has not been well characterized in HFpEF. Recently several studies have described the role of RV in these patients by echocardiography, and few studies by CMR. In these studies,it has been found that addition of RV dysfunction is related with worse prognosis. The following explanation has been proposed: Impaired LV diastolic function causes passive rise in left atrial (LA) pressure and consecutively in PAWP and pulmonary artery (PA) pressure. Pulmonary artery compliance (PAC) decreases and adds to the increasing resistance against the right ventricle.RV fails to compensate pressure overload,dilates and finally RV failure occurs.Left atrial dilation is also present in these patients. Although HFpEF is considered as a disease of the left ventricle,RV dysfunction is also affected. Diabetes Mellitus and hypertension present with HFpEF predominantly, however RV dysfunction is also observed in these patients. Improvement of right heart imaging by echocardiography and CMR will be very helpful in the diagnosis and determining the prognosis.
