Biography:

Savvy Nandal is a Cardiology Registrar at the Northern Hospital in Melbourne, Australia. Her interests include management especially novel therapies of heart failure. Her working experience includes clinical, teaching as well as leadership roles at the teaching hospital.

Abstract:

Heart failure is a major cause of morbilidty and mortality worldwide. PARADIGM-HF study demonstrated Valsartan/ sacubitril (Entresto) decrease HF hospitalisation, cardiovascular mortality and all-cause mortality in patients with HF with reduced ejection fraction (HFrEF). Since addition of Entresto to Australian Pharmaceutical Benefit Scheme in June 2017, there has been considerable uptake of this drug. The aim of this study was to assess efficacy, tolerability and complications of Entresto with real-word evidence. We identified patients who were commenced on Entresto from 1/6/2017 to 30/11/2017 at a tertiary centre in Victoria, Australia via pharmacy dispensing database. 33 patients were commenced on Entresto with median age of 65; median EF was 31% with 57% secondary to ischaemic cardiomyopathy. 27 out of 33 patients were followed up via phone/ clinic/ patient records with three deaths in the time period. There was strong correlation in improvement in quality of life scores (EQ5D), pre vs post: 50 vs 65, (p value <0.05), New York Heart Association (NYHA) class (p value <0.05) and average BP reduction from 119 (101,137) to 110 (95,125) since commencement of Entresto. Commencement dose of Entresto was 24/26 mg in 60% patients and was up titrated in 37%. Only 14% were able to able to achieve recommenced maximal dose (97/103 mg). The commonest side effect was symptomatic hypotension, which led to dose reductions or complete cessation. Our study provides evidence that Entresto results in symptom improvement in addition to BP reduction in patients with HRrEF as well as common side effects of this drug. Further research is required to demonstrate whether these outcomes are sustained in the longer-term as well raise awareness of this novel therapy in the primary care setting.

Recent Publications
1. McMurray J J V, et al (2014) "Angiotensin-neprilysin inhibition versus enalapril in heart failure". The New Englan Journal of Medicine 371(11):993-1004.

Biography:

Konstantin V Pavlov has experience of being Laboratory Assistant, Engineer, Research Engineer, Junior Research Fellow, Regulatory Reviewer, Data Collector, Simultaneous Translator, Research Fellow and Senior Research Fellow at Frumkin Institute of Electrochemistry, Moscow Institute of Physics and Technology, Moscow Institute of Open Education, FMBI Institute of Physical-Chemical Medicine (in-house); Rosatom, Rosenergoatom, US NIHCD, US DOE, UK DTI, WANO, Ministries of Interior, Trade and Industry, Atomic Energy etc. His areas of research with hands-on experience and proven academic record include “Mathematical methods in physics, wet chemistry, electrophysiology, probabilistic risk assessment, metrology, fluorescent microscopy, and two-phase fluid dynamics in systems with non-stationary boundary conditions (flexible pipelines vulnerable to pipe whip, peristaltic systems etc.)”. The general approach assumed for this presentation is simplifying the complex interrelated systems by segmentation or statistical binning, and then discarding the outliers using alternative criteria.

Abstract:

Statement of the Problem: Cardiovascular system connects every organ of living organism through complex network of arteries, veins and capillaries. Tissues with no capillarization (cartilage, bone, and dentine) can exchange with blood through diffusion, and the substances capable of penetrating blood-brain barrier can travel with body fluids to any tissue (on different time scales). This makes pharmaceutic and surgical treatment of cardiovascular diseases closely interdependent with the state and activity of virtually every organ or tissue of organism. Same issues, for similar reasons, complicate diagnostics in cardiology.
Methodology & Theoretical Orientation: Statistical methods and digital simulations applied to non-linear dynamic systems have strong limitations. A hard and costly solution is binning data pools together for similar classes of objects, subsequently using Ishikawa diagrams to discriminate between the essential and non-consequential factors. Use of first physical principles (mechanics, hydrodynamics, thermodynamics, electrodynamics) in analyzing causes of the disease (blood biochemistry, blood flow obstruction, malnutrition, low oxygen or high CO in ambient air, oxidative stress etc.), as well as instruments and methods suitable for diagnostics (number of electrocardiogram leads; electrode and patient preparation, ambient conditions) appears to be another viable solution.
Findings: Theoretical analysis suggests that correlations between blood flow dynamics, elasticity of blood vessels/cell membranes, temperature, and functions of cell signaling receptors (insulin, barocepters, thermosensors etc) can be used to optimize treatment and diagnostics of patients. Experimental evidence supports this hypothesis.
Conclusion & Significance: Prophylactics, diagnostics, invasive surgery, anti-inflammatory treatment, pain medication, nutritional and psychologic support have to be coordinated to achieve the desirable result. Simultaneous use of several alternative methods aimed to protect patient and regulate his functions can be worse than complete absence of medical assistance. Multiple feedbacks, e.g. on physical (hydrodynamics, see above) and subconscious (proper nutrition prevents anxiety, thus ruling out false cardiologic symptoms) levels must be (and are) used by clinicists, as illustrated by examples in the presentation.

Recent Publications
1. S A Akimov, V V Aleksandrova, T R Galimzyanov, Pavel Bashkirov and Oleg V Batishchev (2017). Interaction of amphipathic peptides mediated by elastic membrane deformations. Biochemistry (Moscow) Supplement Series A,
Membrane and Cell Biology 11(3):206-216.
2. Rudenko M, Voronova O, Zernov V Kolmakov S, Makedonsky D, Mamberger K, Rudenko S, Volkov A. Volossatykh O, Khlestunov S and Prikhozhan Y (2009). Theoretical Principles of Heart Cycle Phase Analysis. Fouqué Literaturverlag. Frankfurt a/M. München - London - New York. – 336 Ñ€. ISBN 978-3-937909-57-8
3. T Lang (2006). How to report Statistics in Medicine M.Secic. American College of physicians. Philadelphia. - - 480 p.
4. Eduard V Bocharov, George V Sharonov, Olga V Bocharova and Konstantin Pavlov (2017). Conformational transitions and interactions underlying the function of membrane embedded receptor protein kinases. Biochimica et Biophysica Acta 1859(9 Pt A)
5. Galya Staneva, Denis S Osipenko, Timur R Galimzyanov, Konstantin V Pavlov and Sergey A Akimov (2016). Metabolic Precursor of Cholesterol Causes Formation of Chained Aggregates of Liquid-Ordered Domains. Langmuir, 2016, 32 (6), pp 1591–1600 DOI: 10.1021/acs.langmuir.5b03990

Biography:

Jacob Jamesraj is a senior cardiac surgeon with a special interest in teaching and teaching aids. He has designed training kits for training surgeons in coronary surgery including beating heart surgery, valve replacements and repairs and minimally invasive surgery. He conducts wet lab workshops and conferences. He is well published. He is an avid poet and painter.

Abstract:

Evaluating one’s own distal anastamosis is indispensable not only for the trainee but also the mature coronary surgeon. It provides insight into its betterment at all stages of one’s surgical career. We devised a scoring system that would enable introspection after a practice anastamosis in a wet lab on a bovine heart with an omental vessel for a conduit. The scoring system has three parts with three components in each; performance, organisation, kinetics, coordination finished anastomosis assessed from the outside; shape, lips, leaks, internal view, regularity of structures, tissue protrusion and lumen distortion. This is a reverse scoring system with 100 allotted points from which points are subtracted for imperfections. A systematic analysis of the anastamosis provides insight for improvement.

Biography:

Valéria Paula Sassoli Fazan completed her Graduation from School of Medicine of Ribeirão Preto, University of São Paulo, in 1991 and attended the Neurosurgery Residency Program at the same university. She obtained her MS in Morphology in 1995 and PhD in Neurology in 1999, at the School of Medicine of Ribeirão Preto. Currently, she is an Associate Professor in Department of Surgery and Anatomy and Manager of Microscopy and Morphometry Laboratory at Experimental Surgery Center in the School of Medicine of Ribeirão Preto, University of São Paulo. She is proficient with a wide-range of light and electron microscopy techniques including specimen preparation and handling, vacuum evaporation and autoradiography. She is an expert in Neurosciences, particularly in the fields of “Peripheral nerves and experimental models of neuropathies, digital image processing and analysis, stereology and morphometry.

Abstract:

Statement of the Problem: Hypertension has a negative impact on both central and peripheral nervous system (PNS) morphology and function. For the central nervous system, brain atrophy, loss of nerve cells in cerebrocortical areas, and glial reaction were well documented. The PNS involvement in hypertension is under investigation in our laboratory for several years and the presence of a so called “hypertensive neuropathy” is documented with endoneurial vascular lesions, axonal atrophy and loss of small myelinated fibers. Hypertension is about twice more prevalent in diabetics as in non-diabetics. Despite this common clinical association, the contribution of each isolated entity in the development of neuropathy is still not well understood. We aimed to investigate the presence of peripheral neuropathy in spontaneously hypertensive rats (SHR) and SHR with chronically induced diabetes, using a morphological and morphometric study of the sural nerves.
Methodology: Female SHR, eight weeks old, received a single intravenous injection of streptozotocin (STZ) to induce diabetes. Normotensive Wistar-Kyoto (WKY) and non-diabetic SHR received vehicle. Twelve weeks after the injection, sural nerves were dissected and prepared for light microscopy and myelinated fibers morphometric study.
Findings: Hypertensive rats showed characteristics of small fiber neuropathy and a severe reduction of the number and density or Schwann cells. The association between diabetes and hypertension caused an increase on the average size of the myelinated fibers, pointing to a small fiber loss, associated to axonal atrophy.
Conclusion & Significance: Association of hypertension and diabetes caused more pronounced changes than in the single disease models. The peripheral nerve disorder observed was a complex neuropathy, involving and including both, large and small fibers. Hypertension caused, indeed, an exacerbation of the alterations already observed in experimental models of diabetic neuropathy. Thus, hypertension associated with diabetes affect the structure of the PNS and that association of the two diseases results in an increased risk of nerve damage.

Recent Publications
1. da Silva G A, Mendes V A, Genari A B, Castania J A, Salgado H C and Fazan V P (2016) Recurrent laryngeal nerve alterations in developing spontaneously hypertensive rats. Laryngoscope 126(1):E40-7.
2. Sanada L S, Tavares M R, Sato K L, Ferreira R da S, Neubern M C, Castania J A, Salgado H C and Fazan V P S (2015) Association of chronic diabetes and hypertension in sural nerve morphometry: an experimental study. Diabetol Metab Syndr 7:9.
3. Oliveira F S, Nessler R A, Castania J A, Salgado H C and Fazan V P S (2013) Ultra structural and morphometric alterations in the aortic depressor nerve of rats due to long term experimental diabetes: effects of insulin treatment. Brain Res 1491:197-203.
4. Sanada L S, da Rocha Kalil A L, Tavares M R, Neubern M C, Salgado H C and Fazan V P S (2012) Sural nerve involvement in experimental hypertension: morphology and morphometry in male and female normotensive Wistar-Kyoto (WKY) and spontaneously hypertensive rats (SHR). BMC Neurosci 13:24.
5. Rodrigues A R, Ferreira R S, Salgado H C and Fazan V P S (2011) Morphometric analysis of the phrenic nerve in male and female Wistar-Kyoto (WKY) and spontaneously hypertensive rats (SHR). Braz J Med Biol Res 44(6):583-591.

Biography:

Syed Raza completed his Graduation from Aligarh University in India in 1993. After completing his Post-graduation in Medicine from the same university, he moved to UK for higher specialist studies. He successfully completed MRCP and CCT and later, he was awarded Fellow of the Royal College of Physicians of Edinburgh. He was awarded Professor John Goodwin prize for outstanding performance in Diploma Cardiology exam at Hammersmith Hospital, University of London in 2001. He is currently serving as Consultant in Cardiology and Head of the Department of Medicine at Awali Hospital, Bahrain. He is the Educational Coordinator and Chairman of Resuscitation Committee of the Hospital. He is the Regional Coordinator and Examiner for MRCP exam for the Royal College of Physicians of Edinburgh. He is an external examiner for Arabian Gulf Medical University. He is also the immediate Past Chairman of Medical Advisory Committee.

Abstract:

Introduction: It is neccessary to risk stratify patients of cardiovascular diseases so as to guide and standerdise management. Method: We made use of QRisk 2 (UK) to assess 10 year cardiovascular risk of patients who presented to the cardiology clinic. Each patient’s relevant data were entered in the QRisk2 assessment tool and a 10 year risk was worked out. Based on the obtained figure, further management strategy was planned for that patient.
Analysis & Results: All low risk patients unless contraindicated underwent some kind of stress testing for evidence of reversible ischemia. Decision based of CV risk score to perform CT coronary angiography when deemed apparopriate were utilised for moderate risk category. Majority of high risk patients were considered for catheter based coronary angiography. Similarly, based on CV risk scoring, Aspirin and Statin therapy were started in 34% and 28% patients respectively. Aspirin and Statin therapy if deemed inappropriate were stopped in 12% and 21% patients respectively.
Conclusion: Simple cardiovascular assessment tools are readily available online that can be downloaded for personal use. Using cardiovascular risk assessment tool simplifies clinical decision making. It helps to standerdise treatment and also guides us to avoid harmful, inappropriate and unneccessary treatment. This therefore is very suitable for day to day parctice and works best in the interest of patient safety. Appropriate use of investigations and other resources are used in managing patients further.

Biography:

Manuela Stoicescu is the Consultant in Internal Medicine, PhD, and Assistant Professor at University of Oradea, Faculty of Medicine and Pharmacy, Medical Disciplines Department, Romania.

Abstract:

Objective: The objective of this study is to find the real cause of a young patient with third degree AV block.
Materials & Methods: This study presents the situation of a young patient 27 years old, which presented syncope. The HR was 30bates/min, very severe bradycardia. The EKG showed severe bradycardia 30 bates/minute in context of third degree AV block. So, the patient presented Adams Stokes syncope. The patient was referred to the Cardiovascular Surgery Department and a permanent pace maker was implanted and the patient’s life was saved. The most important question is which was the cause of the third degree AV block with Adams Stokes syncope at young age? Because the patient’s present weakness, asthenia a biopsy of deltoid muscle was performed and shows increased variation in muscle fiber diameter in context of muscular dystrophy of Duchene.
Results & Discussion: This disease is a rare genetic neurological disease. The cause of the third degree AV block at this young patient was in context of this rare genetic neurologic disease - muscular dystrophy of Duchene, confirmed safe by histopathology examination after muscular biopsy.
Conclusion: In conclusion, at young patient with third degree AV block, we must take into account also this rare but possible cause - muscular dystrophy of Duchene.

Biography:

Bhavik Khatri is a 3rd year Cardiovascular Disease fellow at UCSF in Fresno, California. His interests are primarily in the use of non-invasive imaging in diagnoses and management of cardiac patients.

Abstract:

Background & Aim: Tachyarrhythmia induced cardiomyopathy (TIC) is typically diagnosed in a retrospective fashion from the resolution of left ventricular (LV) dysfunction upon recovery from the tachyarrhythmia. At present, our knowledge of echocardiographic diagnostic criteria for TIC is limited.
Methods: From retrospective chart review, we identified 206 consecutive patients presenting with first known episode o atrial fibrillation with rapid ventricular rate and echocardiographic evidence of moderate to severe left ventricular systolic dysfunction (LV EF<40%). A total of 21 were confirmed to have TIC based on the evidence of recovery of LV function with successful rate/rhythm management of the tachyarrhythmia. Workup including coronary angiogram was negative for any other underlying etiology. Clinical and electrocardiographic data were compared among TIC, ICM and NICM groups. We compared TIC group with 41 ischemic (ICM) and 37 non-ischemic cardiomyopathy (NICM) subjects; etiology of NICM was tachyarrhythmia such as drug induced.
Results: For the comparison of groups, analysis of variance (ANOVA) and Kruskal-Wallis test were used for continuous variables and Chi-square analysis for dichotomous variables. Obesity was more prevalent (61.9%) in TIC group. Characteristically, LV geometry (mass and size) was normal in TIC with no regional segmental wall motion or thickening abnormality. Specificity and sensitivity of normal LV morphology (size and mass) with no regional WMA in subjects with reduced EF (<40%) was 84% and 58% respectively for TIC. Compared to TIC and ICM, LV was dilated with eccentric hypertrophy in NICM. Regional segmental abnormality was diagnostic echocardiographic marker of ICM.
Conclusion: In newly diagnosed TIC, LV morphologic features including LV mass, size, myocardial segmental thickness and
wall motion were noted to be normal compared to ischemic and non-ischemic dilated cardiomyopathy.

Biography:

Weiju Zhou is a PhD student in Epidemiology and Global Health Research under the supervision of Prof Ruoling Chen (DoS) at University of Wolverhampton, UK. His research interests are socioeconomic status (SES) and cardiovascular diseases. He examines the data of the Anhui cohort study and the four-province health survey on older population in China, to address important research questions in health inequality. He has co-authored two papers published in peer-reviewed journals.

Abstract:

Background: Older people suffer from more heart diseases (HD) and depression, both of which increase all-cause mortality. It is little known on the impact of HD with depression on survival in older people living in rural areas, where the risks of HD and depression are different from their urban counterparts.
Methods: We examined the Anhui cohort study in China, which consisted of 1600 participants aged >=60 years who live in rural areas life-long. We conducted baseline health survey in 2003 using a standard method of interview, documenting any type of HD and diagnosing any depression (cases and subcases) from the GMS-AGECAT for each participant. In 2004, 2007 and 2011 we successfully re-interviewed surviving cohort members and monitored vital status of the cohort until 2012.
Results: Of 1600 participants, 1429 (89.3%) were followed up, of which 385 deaths were documented. There were significant differences in death rate among participants of having HD and depression (42.3%, 11/26), having HD without depression (35.4%, 23/65), having depression without HD (35.1%, 149/424) and having neither HD nor depression (22.1%, 202/914). After adjustment for age, sex, body mass index, educational level, smoking, alcohol drinking, living with somebody, hypertension, diabetes and stroke at baseline, hazard ratio of all-cause mortality was 2.01 (1.07-3.77) in those having HD and depression, 1.53 (0.99-2.37) in HD only and 1.67 (1.34-2.08) in depression only, compared to those without HD and depression.
Conclusions: Older people living in rural areas with HD and depression had an additional increase in all-cause mortality. Psychological interventions should be taken for those with HD living in rural areas to improve surviving outcome.

Biography:

Yasir Ghareeb Alrashdan is a 5th year Medical student at Hail University, Saudi Arabia. He is the Co-author in this research with his supervisor Dr. M Parvaiz Farshori who has done a lot of important research in medical field.

Abstract:

Introduction: According to the WHO world health ranking survey Saudi Arabia ranked 27th in coronary heart disease (CHD) related deaths. CHD was also the leading cause of deaths in Saudi Arabia (WHO, 2014 survey). One of the major reasons for CHD is tobacco use (WHO bulletin 2016) and the rapidly rising cases of obesity in Saudi Arabia due to consumption of unhealthy diet, lack of exercise or any other physical activity. In the recent past inheritance of ABO blood groups has been linked to various diseases such as diabetes many types of cancers and cardiovascular diseases, although several studies have been published showing the association between the inheritance of blood groups (ABO and Rh antigens) and cardiovascular diseases.
Aim: Since the results of previous studies have been inconsistent regarding the association between the CAD and the inheritance of AB and the Rh (D) blood group antigens, and since according to WHO, CAD is the leading cause of death in Saudi Arabia (WHO 2014 survey), we decided to perform a smaller study on 111 male CHD patients who were admitted in the recent past to the king Khaled hospital (KKH) in the Hail region of Saudi Arabia with an acute myocardial infarction (MI).
Materials & Methods: In the current study we randomly chose 329 male control subjects and 111 myocardial infarction male patients who were enrolled at (KKH) Cardiology Department in Hail region of Saudi Arabia. Other risk factors like diabetes, smoking, age, gender, obesity, family history of CAD. The data was analyzed by Z-test.
Results: Out of 329 randomly selected male control subjects 82% were found to be Rh+ and 18% were Rh- , 3.35 were A-, 20.7% were A+, 3.95 were B- and 14.28% were B+, 2.43% were AB- and 8.2% were AB+, 8.5% were O- and 38.3% were O+. among the MI patients Rh- 4.5% and Rh+ 95.5%, A- were 0.9% and A+ were 30.6%, B- were 1.8% and B+ were 18.01% , AB- were 0.9% and AB+ were 6.3%, O- were 0.9% and O+ were 40.5%.
Conclusions: A+ male patients show statistically high incidences of MI and O- show significantly low incidence of MI.

Recent Publications
1. Al-Dossary S S, Sarkis P E, Hassan A, Ezz E l Regal M and Fouda A E (2010) Obesity in Saudi children: a dangerous reality. East Mediterr Health J 16: 1003-1008.
2. Farshori M P Q, Al-Wakid I H, AL Ibrahim I K, ALShammari A F, Alduejieman M, et al. (2016) Distribution of ABO and Rhesus (Rh) blood group antigens in male type 2 diabetes mellitus patients in Hail region of Saudi Arabia: High incidences of diabetes mellitus in males with B+ blood type. Integr Obesity Diabetes 2: 1-6.
3. Fagherazzi G, Gusto G, Clavel-Chapelon F, Balkau B and Bonnet F (2015) ABO and Rhesus blood groups and risk of type 2 diabetes: evidence from the large E3N cohort study. Diabetologia 58: 519-522.

Biography:

Sami Salahia is a co-founder at MRSA Group and Genome Medical Research Association in the UAE. He is a 5th year medical student at Ain Shams University in Egypt with an interest in medical research and has a number of publications in peer reviewed journals. Being a Team Leader, he gives training to undergraduate
medical students in Egypt and UAE especially for secondary research.

Abstract:

Introduction: Hypertrophic Cardiomyopathy is an inherited disease caused by mutations that occur in B-myosin heavy chain that affects heart muscle proteins. It’s the most common cause of sudden cardiac arrest in Young Athletics. Angiotensin II receptor blockers (ARBs) such as Losartan is a medication that attenuate the myocardial hypertrophy and fibrosis.
Purpose: To systematically review and conduct a meta-analysis of randomized controlled trials investigating the impact of Losartan as Angiotensin receptor blocker on Hypertrophic Cardiomyopathy.
Methods: We searched PubMed, Medline, Scopus, Web of Science and ScienceDirect to detect randomized controlled trials that evaluate the impact of Losartan and ARBs on patients with Hypertrophic Cardiomyopathy.
Results: From a total of 694 entries identified, six RCTs were appropriate for inclusion into the final analysis. The metaanalysis indicated a significant lowering of Systolic blood pressure (mm Hg) compared to Placebo (MD= -7.16, 95% CI [-12.95, -1.36], p=0.02). While the pooled estimate showed no significant difference between Losartan and Placebo regarding Left atrial volume(MD= -5.71, 95% CI [-13.55, 2.14], p=0.15), Left ventricle outflow peak gradient(MD= 1.30, 95% CI [-4.69, 7.29], p=0.67), Left ventricular wall thickness(MD= -1.42, 95% CI [-6.32, 3.48], p=0.57), Left ventricle diastolic diameter (MD= 0.00, 95% CI [-7.10, 7.10], p=1.00), Diastolic blood pressure (MD= -1.00, 95% CI [-9.10, 7.10], p=0.81), NT-proBNP (MD= 7.00, 95% CI [2.04, 11.96], p=0.006). Regarding Tissue Doppler Ea (cm/s), Tissue Doppler Ea/Aa and E/E’ (lateral) The pooled estimate of studies did not differ significantly between the ARB and control group (MD= 2.03, 95% CI [-0.35, 4.42], p=0.09),(MD= 2.00, 95% CI [-0.30, 0.70], p=0.43), and E/E (MD= -2.60, 95% CI [-6.20, 0.99], p=0.16), respectively.
Conclusion: This meta-analysis showed a significant difference of lowering Systolic blood pressure (mm Hg) compared to Placebo while Losartan had no effect on improving the myocardial performance in patients with Hypertrophic Cardiomyopathy.

Recent Publications
1. Salahia S I, Safi O, El-sabbagh A E A, Ellotf H M, Fouda M A, Salahia S I, Ahmed M, et al (2017). PROSPERO International prospective register of systematic reviews Efficacy of tranexamic acid as compared to aprotinin undergoing cardiac surgery with cardiopulmonary bypass systematic review and meta-analysis.
2. Salahia S I, Saad A M, Hilali M F, Alkhaledi A N, Khalaf A R, and Khaled. (2017). A Long-term, T H PROSPERO International prospective register of systematic reviews Long-term versus short-term zoledronic acid for metastatic
breast cancer: a systematic review and meta-analysis.
3. Salahia S, Safi O, Saadeddin A, Mahmoud H, Al-husseini M, Sinokrot M, Al-husseini M et al (2017). PROSPERO International prospective register of systematic reviews Systematic review and meta-analysis of systemic infammatory response syndrome after pediatric congenital heart surgery.
4. Salahia S, Salahia H, Saad A, Haidar L, Rifai N, Ahmed I and Mohamed Y. (2017). PROSPERO International prospective register of systematic reviews Long-term efficacy of antibiotic prophylaxis for preventing recurrent uncomplicated urinary tract infections: a systematic review and meta-analysis.
5. Salahia S, Safi O, Hakmi A A, Mahmoud H, Salahia S, Safi O, Efficacy, A et al (2017). PROSPERO International prospective register of systematic reviews Efficacy and safety of the angiotensin II receptor blocker losartan for hypertrophic cardiomyopathy: Systematic Review and Meta-Analysis.