10^th Global Annual Oncologists Meeting July 11-13, 2016 Cologne, Germany

Dr. Rudolf Schiessel is a Professor of Surgery at Österreichische Gesellschaft für Chirurgie Located at Austria

Pathophysiology of the gastrointestinal tract, Surgical Oncology, Sphinktererhaltung and Sphinkterersatz in rectal

Abdolrahman Shams Nateri Completed his doctrate degree on the genetic engineering of Picornavirus, human Parechovirus 1,at the Essex Univ. later on in the year 2001, he joined as a member of Cancer Research UK (CR-UK) London Research Institute (previously known as ICRF), where he carried out his fundamental basic-research into the links between transcription, MAPKs signaling & diseases, including the cellular/molecular biology of cancer and also rewarded with publications with top journals.In 2007, he joined as a faculty of the UoN, where he intially started as a lecturer, and was promoted as an Associate Professor,his endless passion in cancer-biology and excellent achievements boasted publications in Nature, Science, etc and more recently J Exp Med & Stem Cells.

Gastrointestinal (GI) disorders (both neoplastic & non-neoplastic),Cancer Genetics, Transgenic Murine Technology, Stem Cells, Reprogramming of Cancer Cells and Links between Signalling, Transcription and Diseases,cellular basis of IES cell self-renewal, the interaction of stem cells with their specialized microenvironment (stem cell niche) and the relationship between stem cells and tumorigenesis.

Eckhard Nagel Born in 1960, since September 2010 he is known for the position of Medical Director of the University Hospital Essen. Previously, he was chief physician of General, Visceral and Transplant Surgery and director of the transplant center at Klinikum Augsburg. As managing director of the Institute for Health Care Management and Health Sciences of the University of Bayreuth. Eckhard Nagel studied medicine in Hannover, Vermont, Dumfries, Grenoble and New Hampshire. After completing his doctorate to the Dr. med., He worked as a research assistant and senior physician at the Medical University of Hannover, where he also qualified as a professor in 1997. In addition, he studied philosophy and history in Hannover and received his doctorate in 1995 for Dr. phil. currently he is a member of various committees and working groups of the German Medical Association and since December 2000 Chairman of the Board of the Rudolf Pichlmayr Foundation and leader of Sonderkrankenanstalt »Rehabilitation after organ transplantation - Ederhof" in Stronach, Eastern Tyrol, Austria. Since 2001 he has been in the presidium of the German Protestant Kirchentag and was from 2003 to 2005 President of the Kirchentag Hannover. He was appointed in 2002 by the federal government in the Rürup Commission for Sustainability in Financing the Social Security Systems, was a founding member of the National Ethics Council set up in 2001

His core operational and strategic areas are research and teaching in the area of healthcare management and health sciences along with a strong health economic bias. In his view both areas are closely linked and accordingly teaching is subject to continuous innovation and improvement processes driven by his research programs.

Prof.Ferdinando Agresta has intially started his carrier as an academic lecturer at the School Special ACOI Surgery Laparoscopic and Minimally Invasive to the Advanced Course of Laparoscopic Surgery abdominal wall and he was also the winner of Prize of the President of the Republic in honor of Francesco Crucitti as Best Young Surgeon for 2002 and later on his achievement with the award FOR HONORABLE MENTION - GENERAL SURGERY SCIENTIFIC PAPER,by the Society of Laparoendoscopic Surgeons, in San Francisco in September 2008. 'board-Director of the World Society of Emergency Surgery and Curently he is a member of the Board of Directors of the Italian Society of Endoscopic Surgery (SICE) and the Association of Italian Hospital Surgeons (ACOI).

His basic research interest is in General surgery and critical care, Annals of Surgery, Surgical Endoscopy,Surgical Laparoscopy, Endoscopy & Percutaneous Technique,Digestive Diseases and Sciences.

Czerw Aleksandra, PhD, Expert in the field of health economics, organisation and management in the protection of health, medical services marketing. Assistant Professor at the Public Health Faculty of the Medical University of Warsaw. Author of numerous developments in the field of the strategic management including strategic analysis in the health protection sector. Member of the Regional and Local Analyses Centre. Co-operates with the pharmaceutical sector. Medicinal products marketing strategies consultant. Author of more than 100 national and international publications. Active member of numerous associations including: Polish Public Health Society, Polish Health Science Society, Polish Pharmaceutical Society, Polish Pharmacoecomic Society, Polish Economic Society.

Implementing market mechanisms in healthcare Organisation and management in the protection of health Medicinal product and health services’ marketing Health economics

Ajay Singh, Ph.D., is a tenured Associate Professor of Oncologic Sciences and Head of Health Disparities in Cancer Research Program at the University of South Alabama Mitchell Cancer Institute (USAMCI). Dr. Singh received a Master’s degree in Biotechnology from Aligarh Muslim University and graduated from the Devi Ahilya University, Indore, India. He completed post-doctoral training in the Department of Biochemistry and Molecular Biology at University of Nebraska Medical Center, Omaha, Nebraska. He later joined as a research faculty in the same department, and moved to USAMCI in 2009. Major focus of research in Dr. Singh’s lab is to understand the role of tumor microenvironment (TME) in cancer progression, metastasis and therapeutic resistance. He has received funding from state and several federal agencies (NCI, NSF and DoD) to support his research activities. Dr. Singh also serves on regional, national and international panels to review research proposals for funding considerations.

Major focus of Dr. Singh’s research is to delineate the molecular mechanisms underlying the aggressive and therapy-resistant behavior of cancer cells. In particular, his lab is investigating the role of microRNAs and tumor microenvironment in facilitating growth, epithelial to mesenchymal transition (EMT), metastasis and drug-resistance of pancreatic and prostate tumor cells. Earlier studies of Dr. Singh identified a mucin gene, MUC4, to be of pathological significance in pancreatic cancer progression and metastasis. MUC4 is an aberrantly expressed glycoprotein in pancreatic cancer exhibiting no expression in the normal pancreas. Recently, his team identified a novel microRNA-mediated mechanism involved in its deregulation in pancreatic cancer. Dr. Singh’s research has also revealed that CXCL12-CXCR4 signaling axis, an exemplary of tumor-microenvironment interaction, promotes drug-resistance in pancreatic cancer cells. In additional studies, his group has identified protein phosphatase 2A (PP2A) as a novel therapeutic target in prostate cancer. They have shown that PP2A activity is inversely associated with androgen-independent growth of prostate cancer cells through a novel mechanism, whereby loss of PP2A-mediated checkpoints leads to the activation of Akt and ERK and partially sustains androgen receptor signaling under steroid-deprived condition. Another area of Dr. Singh’s laboratory is to understand the molecular causes of racial disparity in several cancer types. The findings from Dr. Singh’s lab offer potential therapeutic implications for microRNAs, PP2A and tumor-microenvironment in highly aggressive and therapy-resistant pancreatic and/or prostate malignancies.

Seema Singh is an Ass. Professor of Oncologic Sciences at University of South Alabama Mitchell Cancer Institute (USAMCI), Mobile, AL, USA. She earned hers PhD from the University of Aligarh M University, Aligarh India in 2001. After completing her PhD. She carried out postdoctoral research in cancer biology at University of Nebraska Medical Center, Omaha, NE, USA. She joined Mitchell Cancer Institute at The University of South Alabama in 2009 and has been recognized as expert in cancer biology and in cancer pathogenesis in particular.

Primary research interests are to understand the role of inflammatory cytokines in cancer pathogenesis (early and late events), define the mechanistic basis of cytokines function, and delineate pathways regulating their expression and activity. Our long term goal is to translate this knowledge to clinics by developing comprehensive mechanism-based treatment and prevention strategies.

José J. Jiménez-Moleón, Associate Professor of Preventive Medicine and Public Health at the University of Granada. His research subjects deal with the application of epidemiological method to the study of non-communicable diseases, including the etiology of cancer. The scientific production of his research activity stems from 12 competitive research projects (four as principal researcher) and 3 research contracts. This has resulted in 97 full-text scientific articles.

Public Health,Epidemiology, Medical & Health Profession Education,Epidemiology and Public Health,Statistical Analysis,Community Health,Obesity Epidemic, Research Methods.

Professor Anderson holds the Established Chair in Biomedical Sciences at the University of Bradford. She obtained her first degree in the University of Wales and second degrees in the Faculty of Medicine, University of Manchester. She has an H index of 57, 450+ peer-reviewed papers, 8 books, has successfully supervised 26 PhDs, and been a member of editorial boards of 10 international journals. She has been or is Editor in Chief of a book Series on toxicology for J.Wiley and sons and the Royal Society of Chemistry respectively. She gives key note addresses at various international meetings. She is a consultant for many international organisations, such as the WHO, NATO, TWAS, UNIDO and the OECD

Cancer, oxygen radicals, human biomonitoring, unbalanced precursor pools, dietary imbalance, male-mediated developmental defects, nanotoxicology, general toxicology