Biography:

Marco Manfredi is a Pediatrician and Gastroenterologist, carried out his education at Parma University where he has completed his PhD in Pediatric Gastroenterology in 2004. Currently he is working as a Manager of Pediatric Emergency and Assistant Manager in Pediatric Gastroenterology at “Pietro Barilla” Children's Hospital in Parma, Italy. His main fields of interests are Helicobacter pylori infection, celiac disease, gastrointestinal infectious diseases and probiotics. He has published more than 70 papers, included chapters of textbooks. He is the Editor of three textbooks on “Helicobacter pylori Infection”, “Gastrointestinal Endoscopy in Children” and “Probiotics in Children” all published by Nova Science Publishers, New York, USA. He is serving as an Editorial Board Member of several reputed journals like “Clinical Microbiology: Open access” and “Frontiers in Pediatric Gastroenterology and Hepatology” and Expert Reviewer for BMC Gastroenterology, Saudi Journal of Gastroenterology and BMC Case Reports. He is a Member of Italian Society of Pediatric Gastroenterology, Hepatology and Nutrition (SIGENP).

Abstract:

Stomach was considered for many years a sterile environment due to its acid secretion which was thought to represent a barrier against microorganisms’ development. But since the discovery of Helicobacter pylori at early 80's, studies’ regarding gastric microbiota has been evidently increased. Helicobacter pylori are now considered the first trigger for the development of the carcinogenetic cascade that leads to gastric ADK. But it is not solely responsible. It seems that it is a trigger causing the alterations of gastric microbiota that result in the development of ADK. Restoring the gastric microflora or maintaining a physiologic gastric environment could be a way to avoid the carcinogenetic cascade. Furthermore we will highlight the results of our study on probiotics and Helicobacter pylori infection. rnrn