Meet Inspiring Speakers and Experts at our 3000+ Global Conference Series Events with over 1000+ Conferences, 1000+ Symposiums
and 1000+ Workshops on Medical, Pharma, Engineering, Science, Technology and Business.

Explore and learn more about Conference Series : World's leading Event Organizer

Back

Chandrika Murugaiah

Chandrika Murugaiah

Universiti Sains , Malaysia

Title: Evaluation of intestinal damage caused by V. cholerae O139, an in vivo study

Biography

Biography: Chandrika Murugaiah

Abstract

Cholera, a severe form of gastroenteritis, is one of the most widespread diseases in developing countries.The mechanism of intestinal infection caused by V. cholerae O139 remains unclear. In order to exploresome morphological aspects of its infection in the intestine including Peyer's patches, we investigatedthe V. cholerae O139 infection at intestinal site of the rabbit gut-loop model. The electron microscopicanalysis revealed denuded mucosal surface with loss of microvilli and integrity of the surface epithelium.Infection of the intestine with V. cholerae O139 induces destruction of villi, microvilli and lining epithelium with exposure of crypts of Lieberkuhn.